The Science
Lion's Mane Mushroom has been studied in both human clinical trials and preclinical research, with findings centered on its unique capacity to support nerve growth factor production.
A landmark 2009 double-blind, placebo-controlled trial published in Phytotherapy Research found that participants supplementing with Hericium erinaceus showed improvements in cognitive function scores at weeks 8, 12, and 16 of the trial. Scores declined after supplementation stopped, suggesting the benefits were linked to ongoing use (Mori et al., 2009).
Preclinical research has identified hericenones and erinacines as the bioactive compounds responsible for stimulating NGF synthesis. A 1996 study in Biological & Pharmaceutical Bulletin confirmed that water extracts of Hericium erinaceus promoted NGF synthesis in vitro (Kawagishi et al., 1996). Subsequent research confirmed that this NGF-stimulating capacity may support neural network development (Lee et al., 2009).
A 2010 study published in Biomedical Research found that four weeks of Lion's Mane intake was associated with reductions in self-reported feelings of irritability and anxiety in participants (Nagano et al., 2010).
Additional research has explored Lion's Mane's role in supporting peripheral nerve recovery and neuroprotective activity. A 2012 study in Fitoterapia found that aqueous extracts supported regeneration processes in peripheral nerve tissue (Wong et al., 2012).
These are ingredient-level findings from published research. They do not represent product-level claims for FlowVeda®. Review the full body of Lion's Mane Mushroom clinical research here.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
